• Job Type: Support Staff - Union
• Bargaining Unit: SSA
• Regular/Temporary: Regular
• End Date if Temporary:
• Hours Per Week: 35.00
• Standard Work Schedule:
• Building:
• Salary Range: $61,692.40 - $61,692.40

Position Summary

Under the supervision of the Principal Investigator, the Senior Technician will be responsible for carrying out fully planned experiments to study the molecular and cellular mechanisms of neurodegenerative disease in mouse models.

Responsibilities

The Senior Technician will:

• Use conventional biochemical, molecular, cellular, immunohistochemical, and behavioral assays to perform experimental work either independently or in collaboration with postdoctoral research scientists and graduate students.
• Maintenance of mouse colonies, behavioral monitoring of mice, genotyping, drug and gene delivery via IP/ICV injections.
• Dissection of mouse tissue, immunohistochemistry and confocal microscopy. 
• Mammalian tissue culture, transfection and lentivirus/AAV production. 
• Responsible for managing lab inventory and ordering, preparing solutions, and performing other duties necessary to the functioning of the laboratory.

Minimum Qualifications

• Requires a bachelor's degree and at least 1.5 years of related experience or equivalent in education, training and experience. 

Preferred Qualifications

• Knowledge of laboratory procedures for mouse colony handling and genotyping.
• Prior experience with neonatal mouse tissue dissection and immunohistochemical analysis of brain, spinal cord and muscle with cryostat and vibratome sectioning combined with confocal microscopy is highly preferred.
• Bachelor’s degree in biochemistry, molecular biology or neuroscience.

Other Requirements

• Excellent interpersonal and organizational skills, demonstrated attention to detail, and ability to work independently. Strong knowledge of laboratory equipment and ability to keep accurate records.

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Equal Opportunity Employer / Disability / Veteran

Columbia University is committed to the hiring of qualified local residents.