Machine Learning Scientist
Systems Biology
Machine Learning Scientist
- 553189
- Columbia University Medical Center
- Systems Biology
- Full Time
- Opening on: Oct 8 2025
- Grade 106
- Job Type: Officer of Administration
- Bargaining Unit:
- Regular/Temporary: Regular
- End Date if Temporary:
- Hours Per Week: 35
- Standard Work Schedule:
- Building:
- Salary Range: $155,000-$230,000
The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.
Position Summary
The AlQuraishi Lab in the Departments of Systems Biology and Computer Science at Columbia University is seeking a Machine Learning Scientist with a focus on deep learning models for biomolecular systems and drug discovery. Projects span development and training of new neural network architectures, design of active learning experiments in conjunction with experimental collaborators, derivation of scaling laws for biomolecular systems, and other topics. All projects involve interactions with team members in the AlQuraishi lab as well as academic and industry partners in three major consortia: OpenFold, AISB (AI Structural Biology Network), and OpenBind.
Responsibilities
High-level (dependent on specific scientific project):
- Design and train state-of-the-art neural network architectures for biomolecular systems, including prediction of protein-ligand, protein-protein, and antibody-antigen structures and affinities, and protein conformational ensembles.
- Design active learning algorithms and experiments to steer large-scale data acquisition campaigns focused on improving biomolecular models.
- Devise experiments to understand scaling behavior of biomolecular models.
- Curate and prepare datasets, and develop dataset processing algorithms, for in-acquisition and proprietary datasets, including in federated training settings.
Day-to-day:
- Develop new ideas, write code, run experiments, analyze data, and prepare reports.
- Be an active member of one or more highly collaborative teams.
- Stay current with the ultrafast-paced nature of biomolecular machine learning.
- Maintain and enhance external visibility through publishing papers, writing open-source code, and engaging with the scientific community.
Minimum Qualifications
- M.S. in computer science / machine learning, computational biology, or related quantitative fields plus five years of related experience, or equivalent combination of education/experience.
Preferred Qualifications
- Ph.D. in computer science / machine learning, computational biology, or related quantitative fields.
- Extensive machine learning experience, including design, training, and deployment of complex neural architectures.
- Extensive programming experience in Python.
- Strong interpersonal skills, excellent written and verbal communication, and the ability to work effectively in cross-functional teams.
Other Requirements
- N/A
Equal Opportunity Employer / Disability / Veteran
Columbia University is committed to the hiring of qualified local residents.
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