- Requisition no: 520458
- Work type: Full Time
- Location: Morningside
- School/Department: Dept of Biomedical Engineering
- Grade: Grade 12
- Categories: Research (Lab and Non-Lab), Administrative Support
- Job Type: Officer of Administration
- Bargaining Unit:
- Regular/Temporary: Regular
- End Date if Temporary:
- Hours Per Week: 35
- Salary Range:
Research Engineer ( grant funded) position (Laboratory for Stem Cells and Tissue Engineering) in the Biomedical Engineering Department at Columbia University, directed by Dr. Gordana Vunjak-Novakovic, is responsible for responding to the critical needs of the existing and new research/developmental projects. The laboratory is the home of the national resource center for tissue engineering, that is funded by NIH to foster the research and development for advanced tissue engineering technologies, and to provide the research community with tissue engineering tools (biomaterials, bioreactors, experimental methods, software), through collaboration, training, service and outreach activities. The laboratory seeks to hire a skilled and talented research engineer to meet the design and fabrication needs of the lab. This position will provide technical advising, engineering design and fabrication services to the Laboratory for Stem Cells and Tissue Engineering, as well as administration oversight for assigned engineering area within the lab. Strong technical operational expertise is required in the design and fabrication of biomaterial scaffolds and bioreactors for tissue engineering, and in the related computer aided design and manufacturing.
(30%) Design cell and tissue culture systems for the broad spectrum of research needs – The scope of research in laboratory involves several broad areas: (1) Bioengineering of the lung for studies of regeneration and cell therapy; (2) Cardiac tissue engineering for studies of cardiac injury and regeneration; (3) Engineering of bone and cartilage grafts for regenerative medicine applications; (4) ”Organs on a chip” platforms for studies of human physiology in health and disease.
(20%)Fabricate serial prototypes and finalized versions of culture systems for whole organ regeneration – For bioengineering of the lung, the experiments are being done in whole lung bioreactors, as well as the small and large animal models. In all cases, the current working prototypes of the equipment and instrumentation will need to be further refined to improve microenvironmental control of the flow and transport and to extend the scope of on-line measurements of functional parameters. For bioengineering of cartilage/bone grafts, the key need is to streamline the design and fabrication of anatomically shaped biomaterial scaffolds and bioreactors using imaging-guided fabrication methods. In both areas, serial prototypes of culture systems and their components will need to be fabricated and made available for use in experiments, with feedback for further improvements of the designs.
- (20%)Fabricate serial prototypes and finalized versions of “organs on a chip” platforms – This roel will support the continued optimization of our “organs on a chip” platforms that consist of the individual tissue chambers (liver, bone, bone marrow, heart muscle, lung, skeletal muscle, solid tumors, vasculature) connected by vascular perfusion. The fabrication aspects need to support the design of the individual tissue chambers, the connections of the chambers, and the modularity of the platforms.
- (15%) Administer and oversee the functionality of laboratory equipment and instrumentation –Maintain the functionality of a large spectrum of laboratory equipment, through inventory and assets management and tracking, regular testing and calibration, preventive maintenance, upgrades and repairs and any necessary troubleshooting. Assist with optimizing effective workflow for usage of equipment and instrumentation. Duties will include tracking budget vs actual expenses, initiation or purchase orders, extension of warranties, and related tasks as needed.
- (10%) Administer and oversee organization of fabrication facilities (bioreactor room, tool room, electronics): Inventory and assets management and tracking, regular maintenance and continued improvements of our key resources for manufacturing tissue culture and testing equipment (bioreactor room), microfabrication tools (tool room) and electronic components and systems for regulation of tissue function, collection and analysis of experimental data (electronics room). Duties will include tracking budget vs actual expenses, initiation or purchase orders, extension of warranties, and related tasks as needed.
- (5%) Perform other administrative / engineering and related duties and responsibilities as assigned/requested
Bachelor’s degree in bioengineering or related field and at least 3-5 years of related experience are required.
Ability to work independently with minimal supervision.
Quantitative skills that are essential for this position.
Ability to prioritize tasks.
Excellent interpersonal, communication, organizational, and computer skills.
Flexibility in terms of working hours in keeping with changing priorities and deadlines.
Ability to manage multiple projects simultaneously
These studies require specialized designs of culture systems that are being developed in close collaboration with investigators, the research engineer must have deep knowledge of engineering design principles and methodologies, ability to follow and accommodate specific biological and technical requirements, and to effectively work with the research teams
Master’s degree in bioengineering or related field and at least 3-5 years of related experience preferred .
Microsoft Office (Word, Excel, Power Point); SolidWorks (+Mastercam for SolidWorks); CNC Controls (Haas Control, Mach 3)
Columbia University will require COVID vaccination for all Columbia University members who will have any on-campus presence. Individuals may claim exemption from the vaccine requirement for medical or religious reasons. More information regarding the University’s COVID vaccination requirement and exceptions may be found at the University’s “COVID-19 Vaccine Information” webpage: https://covid19.columbia.edu/ . Compliance with these measures is mandatory
Equal Opportunity Employer / Disability / Veteran
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